Rare Donor Register
Erythrocytes from donors and patients have numerous different blood group antigens. If antibodies against these antigens are present, the donor blood must be compatible with that of the recipient, otherwise transfusion reactions may be triggered in the recipient.
For patients with the most common blood groups, the rapid and cost-efficient supply of compatible red blood cell concentrates is now a matter of course.
However, patients with rare phenotypes who have formed the corresponding alloantibodies against them represent a special category.
In order to be able to supply these patients with blood in time, great efforts are usually required, for example to find compatible donors at national or international level. Examples of such rare phenotypes are the absence of high-frequency antigens such as k, Kp(b) (KEL4), Lu(b) (LU2), Co(a) (CO1), Vel (VEL1), Yt(a) (YT1), P (GLOB1), Lan (LAN1), Jr(a) (JR1) or U (MNS5) or the rare phenotypes K0,(KEL:-5) Lu(a-b-) (LU:-1,-2), Jk(a-b-) (JK:-1,-2) and Rhnull.
